Psychedelic amphetamines make up the bulk of the “entactogen” class of drugs. They work by altering the chemistry of our brains to induce feelings of pleasure and motivation, enhance our ability to empathize with others, and increase energy levels.
Amphetamines are a class of central nervous system stimulants. Some are used as a treatment for ADHD, obesity, Parkinson’s disease, or narcolepsy; others are used as recreational drugs.
All amphetamines are derived from the basic amphetamine molecule. New amphetamine derivatives are made by swapping one or more of the hydrogen atoms attached to the central structure with other functional groups.
The effects of amphetamines vary from being stimulating like caffeine, to psychedelic like mescaline — and everything in between. Most amphetamines act as stimulants and euphorics (mood-enhancers).
Each of our neurons has a collection of receptors located within the synapses. A synapse is the point of contact between neurons where information is passed. Neurons pass this information in the form of chemical messengers called neurotransmitters such as dopamine, norepinephrine, or serotonin.
Once a neurotransmitter is passed from one neuron to the next, it binds to a receptor and causes an effect. Once finished, it’s reabsorbed into the neuron, where it’s broken down and recycled.
Amphetamines work by altering one or more of these processes — leading to an accumulation of neurotransmitters and an increased excitatory (stimulated) state.
The DOX compounds are among the strongest amphetamines ever discovered. They’re the only group of substituted amphetamines that are active at the sub-milligram dose. Because of how potent these compounds are, they’re usually sold in blotter paper form rather than in capsules or powder. Compounds such as DOB, DOI, DOC, DOPR, DOEF, and DON are all psychoactive in doses around 1 mg or less.
Synthetic cathinones are another powerful group of amphetamines. Compounds such as MDPV, α-PPP, and α-PVP are all active around the 3–5 mg mark.
The MDXX group, which is home to MDMA and MDA, is the least potent overall — most of the compounds in this group aren’t active until roughly the 50 mg mark.
Each amphetamine has a different half-life, which describes the amount of time it takes for half the substance to be removed from the body. Most amphetamines are eliminated through urine, so traces of the compound may remain detectable for as long as the drug remains in the system.
Most amphetamines are undetectable in the urine within 1 week. Some, such as Adderall (amphetamine), have a very short half-life and may be eliminated as quickly as 24 hours.
Addiction to stimulant drugs is common — you are not alone. The first step to getting help is to reach out to either a doctor, a family or friend or one of the addiction hotlines listed below.
Depending on where you live, it may take some time to get treatment. It’s wise to start the process now, even if you don’t think you’re completely ready to quit yet.
Kicking amphetamine addiction isn’t easy, but there are services available to help reduce the discomfort of withdrawals and get you back on your feet — you just have to ask for it.
The fluorinated amphetamines first started appearing on the market around 2010. The most common members of this group include 2-FMA, 2-FA, and 4-FA.
These are characterized by a fluoride group attached to the central ring moiety of the base amphetamine molecule. The addition of fluorine significantly alters the bioavailability and selectivity of a substance on various receptors — often unpredictably.
Unfortunately, fluorinated substances also release radioactive fluoride atoms into the brain, which can cause long-term cognitive problems.
In every batch of our Psychedelic Amphetamine we supply throughout the word, we place a high priority on quality. Our strict guidelines guarantee that researchers receive dependable, precisely characterised materials supported by thorough testing and complete regulatory awareness.
