4-FA Powder (4-Fluoroamphetamine)

High-Purity Research Compound | Analytical Reference Standard | CAS 459-02-9

Product Overview

Welcome to our premier product listing for 4-FA Powder, a high-purity chemical compound available exclusively for advanced scientific and laboratory research. As a trusted research chemical supplier, we provide materials that meet the highest industry standards for analytical precision, ensuring reliable and reproducible results for your institutional studies.

Also known as 4-fluoroamphetamine, this compound is a synthetic stimulant of the amphetamine class. Its chemical structure is very close to that of the amphetamine molecule, differing only by the presence of a fluorine atom at the para position of the phenyl ring [citation:12]. Depending on your field of study, 4-FA serves as a critical reference material for neuroscience pharmacology and psychopharmacology research. Whether you are investigating fluorinated amphetamines or conducting comparative isomer studies, this 4-FA research chemical provides the integrity your lab requires. We offer high purity 4-FA powder with certificates of analysis available upon request. For a full range of research compounds, browse our catalog here.

Key External Resources:
ChemSpider – 4-Fluoroamphetamine Properties |
NCATS Inxight Drugs – Pharmacological Data |
Jellinek – Effects and Risks

What is 4-FA Powder?

4-FA Powder is a synthetic fluorinated compound belonging to the amphetamine class. The systematic name is 1-(4-fluorophenyl)propan-2-amine. It is a fluorinated amphetamine analog that acts as a potent stimulant and empathogen, with effects similar to MDMA and amphetamines [citation:3][citation:12].

In the brain, 4-fluoroamphetamine influences the neurotransmitters dopamine, noradrenaline, and serotonin [citation:3]. It functions as a dopamine reuptake inhibitor research tool and also inhibits the reuptake of serotonin and noradrenaline [citation:12]. Our product is widely utilized as a 4-FA analytical reference standard and a pharmaceutical intermediate for the synthesis of complex molecules. With a defined 4-FA CAS 459-02-9 profile or 4-FA hydrochloride CAS 459-01-8 specifications, this compound is indispensable for modern laboratories.

Chemical Properties Reference:
4-Fluoroamphetamine Structure and Properties on ChemSpider

Key Uses & Applications

Our 4-FA powder research chemical stimulant capabilities make it a versatile asset for several specialized fields. Visit our main research chemicals homepage to explore related products.

1. Neuroscience & Psychopharmacology

Researchers utilize 4-FA to study central nervous system activity. It is used in 4-FA in vivo locomotor activity study and 4-FA discriminative stimulus effects research to evaluate abuse liability. Common applications include:

• 4-FA vs methamphetamine comparison study to assess potency and efficacy [citation:6].
• 4-FA positional isomer pharmacology to understand the impact of fluorine position [citation:6].
• 4-FA regioisomer abuse liability potential for drug discrimination assays [citation:6].
• 4-FA serotonin release mechanism and 4-FA noradrenaline reuptake inhibition study [citation:3][citation:12].
• 4-FA psychoactive effects in animal models for behavioral research [citation:6].

Further Reading:
UNTHSC Study: Locomotor and Discriminative Stimulus Effects

2. Toxicology & Safety Research

For toxicology and risk assessment, 4-fluoroamphetamine is studied to understand its adverse effects. Key applications include:

• 4-FA cardiovascular adverse effects research to analyze heart rate and blood pressure changes [citation:3].
• 4-fluoroamphetamine neurotoxicity study to assess potential long-term damage [citation:12].
• 4-FA hyperthermia risk assessment for warm environments [citation:3].
• 4-FA cerebrovascular effects study including headache and brain bleeding risks [citation:3].
• 4-FA health incident reports and 4-FA pharmacological safety data analysis [citation:3][citation:6].

3. Analytical & Forensic Reference Standards

Our 4-FA for in vitro studies and 4-FA online research compound is essential for:

• 4-FA purity testing HPLC and 4-FA GC-MS analysis [citation:7].
• 4-FA reference standard for forensic toxicology [citation:10].
• 4-FA structure-activity relationship (SAR) studies for drug development [citation:6].

For more information on our quality standards, learn about our lab testing protocols.

Health & Safety Considerations (Research Context)

• Neurotoxicity: 4-fluoroamphetamine differs from other halogenated amphetamines like 4-chloroamphetamine and is considered less neurotoxic, but caution is still required [citation:12].
• Cardiovascular Risks: 4-FA overdose risk analysis shows that high doses can lead to cardiac arrhythmias, dangerously high blood pressure, and respiratory problems [citation:3].
• Hyperthermia: 4-FA safety profile for research indicates that body temperature rises significantly, and in warm environments, overheating (hyperthermia) can occur, which is life-threatening [citation:3].
• Solubility: We provide data on 4-FA hydrochloride solubility and other solvent compatibility to ensure accurate assay preparation.
• Storage: Store in a cool, dry, dark place away from moisture and light. 4-FA long-term effects research is ongoing, so proper handling is critical.

Safety Reference:
NCATS Inxight Drugs – UNII YIJ78M8D5Q |
Jellinek – Detailed Effects and Risks

Technical Specifications & Purity

• Chemical Name: 4-Fluoroamphetamine
• Synonyms: 4-FA, 4-FMP, 1-(4-Fluorophenyl)propan-2-amine [citation:4][citation:8]
• CAS Number: 459-02-9 (Freebase) | 459-01-8 (Hydrochloride) [citation:8][citation:10]
• Molecular Formula: C9H12FN [citation:4]
• Molecular Weight: 153.197 g/mol [citation:4]
• InChIKey: DGXWNDGLEOIEGT-UHFFFAOYSA-N [citation:8]
• Boiling Point: 215°C [citation:4]
• Density: 1.042 g/cm³ [citation:4]
• Purity Level: >99% (HPLC verified)
• Form: Crystalline or fine powder
• Storage: Store in a cool, dry, dark place away from moisture and light.

Why Choose Our 4-FA Powder?

• Verified Purity: We provide 4-FA research chemical for sale with full transparency, including HPLC and GC-MS reports. View our quality assurance process.
• Versatility: Usable for 2-FA vs 3-FA vs 4-FA comparison, 4-FA vs MDMA effects research, and 4-FA vs 4-FMA research.
• Reliable Sourcing: We are a trusted 4-FA online research compound supplier for universities and private R&D institutions. See our partner institutions.
• Competitive Pricing: Buy 4-FA powder for research at industry-leading rates without compromising quality.
• Bulk Availability: Whether you need a small sample for 4-FA for laboratory use or bulk quantities for 4-FA toxicity in animal models, we accommodate all scales.

How to Use in the Lab

1. For Pharmacological Studies: Prepare specific concentrations for 4-FA in vivo locomotor activity study or 4-FA discriminative stimulus effects research in animal models [citation:6].
2. For Receptor Binding Assays: Dissolve in appropriate buffer for 4-fluoroamphetamine dopamine reuptake inhibitor research and 4-FA serotonin release mechanism studies [citation:12].
3. For Reference Standards: Use directly for 4-FA analytical reference standard calibration and 4-FA GC-MS analysis [citation:7].

For detailed protocols, visit our application notes section.

Frequently Asked Questions (FAQs)

Q: What is the difference between 2-FA, 3-FA, and 4-FA?
A: The position of the fluorine atom on the benzene ring changes the compound’s potency, efficacy, and pharmacological profile. 4-FA positional isomer pharmacology studies show that while 2-FA and 3-FA produce effects similar to methamphetamine, 4-FA has a distinct empathogenic profile [citation:6][citation:12].

Q: Can I buy this for human use?
A: No. This product is strictly classified as a 4-FA research chemical. It is sold as a pharmaceutical intermediate and laboratory reagent solely for scientific investigation. Review our intended use policy.

Q: What are the known risks of 4-FA?
A: 4-FA cardiovascular adverse effects research indicates risks including increased heart rate, hypertension, and in severe cases, cerebral hemorrhage. 4-FA hyperthermia risk assessment is also a key area of research [citation:3].

Q: Do you offer bulk discounts?
A: Yes. Please contact our sales team for pricing on large orders.

Research References:
UNTHSC Study on Locomotor Effects |
NCATS Inxight Drugs – UNII Data

Order Your 4-FA Powder Today

Advance your research with confidence. Whether you are conducting 4-FA vs methamphetamine comparison study, exploring 4-FA vs MDMA effects research, or performing 4-FA regioisomer abuse liability potential analysis, our 4-FA is the premium choice.

Keywords to remember: 4-FA CAS 459-02-9, 4-fluoroamphetamine molecular weight 153.197, high purity 4-FA powder, 4-FA research chemical stimulant, and 4-FA online research compound.