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3-FPM Powder (3-Fluorophenmetrazine)
High-Purity Research Compound | Analytical Reference Standard | CAS 1803562-83-5
Product Overview
Welcome to our premier product listing for buy 3-FPM powder for research, a high-purity chemical compound available exclusively for advanced scientific and laboratory research. As a trusted research chemical supplier, we provide materials that meet the highest industry standards for analytical precision, ensuring reliable and reproducible results for your institutional studies.
Also known as 3-fluorophenmetrazine and PAL-593, this compound is a phenylmorpholine-based stimulant and a fluorinated analogue of phenmetrazine. Its chemical structure is closely related to the anorectic medication phenmetrazine, which was once prescribed but later withdrawn due to its abuse potential. Depending on your field of study, 3-FPM serves as a critical reference material for neuroscience pharmacology, psychopharmacology, and forensic toxicology research. This 3-FPM research chemical for sale provides the integrity your lab requires for investigating novel psychoactive substances (NPS) and psychostimulant compounds. We offer high purity 3-FPM powder with certificates of analysis available upon request. For a full range of research compounds, browse our catalog here.
Key External Resources:
ScienceDirect – Monoamine Transporter Pharmacology Study |
PubMed – Synthesis and Characterization |
MuseChem – Technical Specifications
What is 3-FPM Powder?
3-FPM Powder is a synthetic compound belonging to the phenylmorpholine class. The IUPAC name is 2-(3-fluorophenyl)-3-methylmorpholine. It is a fluorinated phenmetrazine analog that acts as a potent norepinephrine-dopamine releasing agent (NDRA), promoting wakefulness, focus, and alertness.
In the brain, 3-fluorophenmetrazine acts as a substrate-type releaser at the dopamine transporter (DAT) and norepinephrine transporter (NET), with IC50 values comparable to cocaine (< 2.5 μM). It functions as a dopamine transporter inhibition tool and a norepinephrine reuptake inhibition study agent, with much weaker effects at the serotonin transporter (SERT). Our product is widely utilized as a 3-FPM analytical reference standard and a pharmaceutical intermediate for the synthesis of complex molecules. With a defined 3-FPM CAS 1803562-83-5 profile or 3-FPM hydrochloride CAS 1803562-83-5 specifications, this compound is indispensable for modern laboratories.
Chemical Properties Reference:
MuseChem – 3-Fluorophenmetrazine Hydrochloride Specifications
Key Uses & Applications
Our 3-FPM powder research chemical stimulant capabilities make it a versatile asset for several specialized fields. Visit our main research chemicals homepage to explore related products.
1. Neuroscience & Pharmacology Research
Researchers utilize 3-FPM to study central nervous system activity and monoamine transporter interactions. It is used in 3-FPM monoamine release assay and 3-FPM transporter-mediated reverse transport studies to understand its amphetamine-like mechanism of action. Common applications include:
- 3-FPM vs 2-FPM pharmacology and 3-FPM vs 4-FPM isomer comparison to understand the impact of fluorine position on potency.
- 3-FPM NDRA mechanism of action studies for drug development and structure-activity relationships.
- 3-FPM amphetamine-like mechanism research to evaluate catecholamine transporter selectivity.
- 3-FPM behavioral pharmacology research and 3-FPM psychostimulant effects in animal models.
- 3-FPM phenmetrazine analog research for comparative pharmacology.
Further Reading:
ScienceDirect – Comprehensive 3-FPM Pharmacology Study
2. Functional Stimulant & Cognitive Research
For cognitive and functional stimulant research, 3-fluorophenmetrazine has been studied for its potential to enhance cognitive function, increase energy levels, and improve mood. Key applications include:
- 3-FPM cognitive enhancement study and 3-FPM focus and concentration effects research.
- 3-FPM wakefulness and alertness research for sleep deprivation studies.
- 3-FPM productivity research and 3-FPM motivation enhancement study.
- 3-FPM functional stimulant properties vs recreational use comparison.
- 3-FPM stimulant effect duration analysis for pharmacokinetic research.
3. Analytical & Forensic Reference Standards
Our 3-FPM for in vitro studies and 3-FPM online research compound is essential for:
- 3-FPM purity testing HPLC and 3-FPM GC-MS analysis.
- 3-FPM NMR characterization and 3-FPM reference standard for forensic toxicology.
- 3-FPM positional isomer differentiation for forensic identification of 2-FPM and 4-FPM.
For more information on our quality standards, learn about our lab testing protocols.
Health & Safety Considerations (Research Context)
⚠️ IMPORTANT LEGAL NOTICE:
This product is strictly for in vitro and animal model research only. It is not intended for human consumption, dietary supplementation, or clinical therapy. 3-FPM has no recognized therapeutic use and is not under international control but is subject to surveillance by the WHO. By purchasing, you agree to our terms and conditions and confirm you have the necessary permits for research.
- Neurotoxicity: 3-FPM neurotoxicity study research is ongoing, but as a potent catecholamine releaser, it has a high potential for abuse and addiction similar to amphetamine-type substances.
- Cardiovascular Risks: 3-FPM cardiovascular adverse effects include tachycardia, hypertension, and palpitations.
- Psychiatric Effects: 3-FPM agitation and delirium study research indicates potential for anxiety, agitation, and delirium at high doses.
- Seizure Risk: 3-FPM seizure risk analysis has documented seizures in some case reports.
- Abuse Liability: 3-FPM abuse liability potential and 3-FPM dependence potential research indicate a risk profile similar to classical psychostimulants.
- Storage: Store at -20°C, away from moisture and light. 3-FPM safety profile for research is still being established, so proper handling is critical.
Safety Reference:
WHO ECDD – International Drug Scheduling Information |
MuseChem – Storage and Handling Information
Technical Specifications & Purity
- Chemical Name: 3-Fluorophenmetrazine
- Synonyms: 3-FPM, 3-FPH, PAL-593, 2-(3-Fluorophenyl)-3-methylmorpholine
- CAS Number: 1803562-83-5 (Hydrochloride)
- Molecular Formula: C11H14FNO (Base) | C11H15ClFNO (Hydrochloride)
- Molecular Weight: 195.24 g/mol (Base) | 231.69 g/mol (Hydrochloride)
- Boiling Point: 280.6°C
- InChIKey: VHYVKJAQSJCYCK-UHFFFAOYSA-N
- Purity Level: ≥95% (HPLC verified)
- Form: White crystalline powder (Hydrochloride)
- Storage: Store at -20°C, away from moisture and light
- Solubility: Water-soluble as hydrochloride salt
Why Choose Our 3-FPM Powder?
- Verified Purity: We provide 3-FPM research chemical for sale with full transparency, including HPLC and GC-MS reports. View our quality assurance process.
- Versatility: Usable for 3-FPM dopamine transporter inhibition, 3-FPM norepinephrine reuptake inhibition study, and 3-FPM NDRA mechanism of action research.
- Reliable Sourcing: We are a trusted 3-FPM online research compound supplier for universities and private R&D institutions. See our partner institutions.
- Competitive Pricing: Buy 3-FPM powder for research at industry-leading rates without compromising quality.
- Bulk Availability: Whether you need a small sample for 3-FPM for laboratory use or bulk quantities for 3-FPM abuse liability potential studies, we accommodate all scales.
How to Use in the Lab
- For Pharmacological Studies: Prepare specific concentrations for 3-FPM monoamine release assay or 3-FPM transporter-mediated reverse transport research in HEK293 cells or rat brain synaptosomes.
- For Receptor Binding Assays: Dissolve in appropriate buffer for 3-fluorophenmetrazine dopamine transporter inhibition and 3-FPM norepinephrine reuptake inhibition study.
- For Reference Standards: Use directly for 3-FPM analytical reference standard calibration and 3-FPM GC-MS analysis.
For detailed protocols, visit our application notes section.
Frequently Asked Questions (FAQs)
Q: What is the difference between 3-FPM and its isomers?
A: The position of the fluorine atom on the phenyl ring changes the compound’s pharmacological profile. 3-FPM vs 2-FPM pharmacology and 3-FPM vs 4-FPM isomer comparison studies show that moving the fluoro substitution from the 2- to 3- to 4-position produces a stepwise increase in potency at SERT relative to DAT and NET.
Q: Can I buy this for human use?
A: No. This product is strictly classified as a 3-FPM research chemical. It is sold as a pharmaceutical intermediate and laboratory reagent solely for scientific investigation. Review our intended use policy. 3-FPM has no recognized therapeutic use.
Q: What are the known risks of 3-FPM?
A: 3-FPM cardiovascular adverse effects include tachycardia and hypertension. 3-FPM agitation and delirium study research documents psychiatric effects. 3-FPM seizure risk analysis has documented seizures in some case reports.
Q: What is the legal status of 3-FPM?
A: 3-FPM is not currently under international control but is under surveillance by the WHO. It is illegal in some countries including Sweden and Switzerland, and scheduled in Virginia, USA. Researchers must ensure they have proper permits and authorizations before purchasing.
Q: Do you offer bulk discounts?
A: Yes. Please contact our sales team for pricing on large orders.
Research References:
ScienceDirect – In Vitro Pharmacology Study |
PubMed – Synthesis and Analytical Characterization
Order Your 3-FPM Powder Today
Advance your research with confidence. Whether you are conducting 3-FPM functional stimulant properties studies, exploring 3-FPM amphetamine-like mechanism research, or performing 3-FPM positional isomer differentiation for forensic toxicology, our 3-FPM is the premium choice.
Keywords to remember: 3-FPM CAS 1803562-83-5, 3-fluorophenmetrazine molecular weight 195.24, high purity 3-FPM powder, 3-FPM research chemical stimulant, and 3-FPM online research compound.
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